Bladder Cancer Involving Smooth Muscle of Indeterminate Type or Muscularis Mucosae in Transurethral Biopsy Specimens

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Transurethral resection specimens of the bladder: outcome of invasive urothelial cancer involving muscle bundles indeterminate between muscularis mucosae and muscularis propria.

OBJECTIVES Thin muscle fibers on transurethral resection of the bladder (TURB) can represent either muscularis propria destroyed or splayed by urothelial carcinoma or muscularis mucosae, which can be hyperplastic. METHODS The data from 94 patients with invasive bladder cancer seen at our institution (1986-2008) with a mean of 25.4 months of follow-up, who had had an uncertain pathologic diagn...

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Unique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder.

The muscularis mucosae, a type of smooth muscle located between the urothelium and the urinary bladder detrusor, has been described, although its properties and role in bladder function have not been characterized. Here, using mucosal tissue strips isolated from guinea pig urinary bladders, we identified spontaneous phasic contractions (SPCs) that appear to originate in the muscularis mucosae. ...

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Antigenic Profile of Muscularis Mucosae and Muscularis Propria of the Urinary Bladder

Background: Differentiation between the muscularis mucosae (MM) and muscularispropria (MP) of the bladder remains challenging. Objective: To identify MM- and MP-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. Method: The expression of 12 protein antigens in 11 human bladder specimens was examined. There were 5 post radical cystectomy specim...

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Muscularis mucosae - the forgotten sibling.

Lamina muscularis mucosae sitting beneath mucosal surface of the digestive tract has received little attention to date compared with external smooth muscle layers. Motor activity of the muscularis mucosae shows a great regional and species difference. Autonomic innervation profile is also different from esophagus to colon or between animal species. Intracellular transduction mechanisms for moto...

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antigenic profile of muscularis mucosae and muscularis propria of the urinary bladder

background: differentiation between the muscularis mucosae (mm) and muscularispropria (mp) of the bladder remains challenging. objective: to identify mm- and mp-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. method: the expression of 12 protein antigens in 11 human bladder specimens was examined. there were 5 post radical cystectomy specim...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2020

ISSN: 0002-9173,1943-7722

DOI: 10.1093/ajcp/aqaa030